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Cumulative upkeep—An opponent gains 1 life. (At the beginning of your upkeep, put an age counter on this permanent, then sacrifice it unless you pay its upkeep cost for each age counter on it.)
This will be pretty damn amazing with Magic Origin's Tainted Remedy.
You'll want to go W for Beacon of Immortality's insta-death anyways, so might as well add this excellent two-drop to hold off the aggro and drop Tainted Remedy next turn.